DNA repair - significado y definición. Qué es DNA repair
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Qué (quién) es DNA repair - definición


DNA repair         
  • DNA ligase, shown above repairing chromosomal damage, is an enzyme that joins broken nucleotides together by catalyzing the formation of an internucleotide [[ester]] bond between the phosphate backbone and the deoxyribose nucleotides.
  • A chart of common DNA damaging agents, examples of lesions they cause in DNA, and pathways used to repair these lesions. Also shown are many of the genes in these pathways, an indication of which genes are epigenetically regulated to have reduced (or increased) expression in various cancers. It also shows genes in the error-prone microhomology-mediated end joining pathway with increased expression in various cancers.
  • Most life span influencing genes affect the rate of DNA damage.
  • DNA repair rate is an important determinant of cell pathology.
  • The main double-strand break repair pathways
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  • Paul Modrich talks about himself and his work in DNA repair.
  • Structure of the base-excision repair enzyme [[uracil-DNA glycosylase]] excising a hydrolytically-produced uracil residue from DNA. The uracil residue is shown in yellow.
PROCESS OF RESTORING DNA AFTER DAMAGE
Dna repair; DNA Repair; DNA damage; DNA repair genes; Excision repair; Excision repair mechanism; Dna repair enzymes; Dna repair-deficiency disorders; Dna repair genes; Double-strand breaks; Double-strand break; Types of DNA lesions; Double strand breaks; Translesion synthesis; DNA damage checkpoint; Double strand break; Self-repair mechanisms; DNA repair gene; Single strand break; Single-strand break; DNA damage checkpoints; DNA lesions; DNA lesion; Translesion; Translation polymerase; DNA-damage response; DNA repair-deficiency disorders; Translesion DNA synthesis; Double-stranded break; Single-stranded break; DNA damage repair
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in tens of thousands of individual molecular lesions per cell per day.
DNA Repair (journal)         
PEER-REVIEWED SCIENTIFIC JOURNAL
DNA Repair (Amst.); DNA Repair (Amsterdam); DNA Repair (Amst); DNA repair (journal)
DNA Repair is a peer-reviewed scientific journal that covers cellular responses to DNA damage. Published monthly since January 2002 by Elsevier as the continuation of Mutation Research/DNA Repair, with Samuel H.
DNA Repair and Mutagenesis         
COLLEGE-LEVEL TEXTBOOK ABOUT DNA REPAIR AND MUTAGENESIS
DNA Repair and Mutagenesis (textbook)
DNA Repair and Mutagenesis is a college-level textbook about DNA repair and mutagenesis written by Errol Friedberg, Graham Walker, Wolfram Siede, Richard D. Wood, and Roger Schultz.
Ejemplos de uso de DNA repair
1. Certain processes like cell division and DNA repair happen at regular times.
2. Research shows that chemicals found in the vegetables can boost DNA repair in cells to prevent them creating tumours.
3. In particular, three genes associated with DNA repair had reduced activity levels in smokers which did not return to normal after they gave up the habit.
4. They found that the over–45s had a different gene pattern, particularly for genes involved in cell death and in DNA repair.
5. It has already revealed that genes involved in DNA repair are not as diverse as those which play a role in the body‘s immune response.